Table 2. Dose-dependent inhibitory effects of 4-OH-TAM on MCF-7 cell growth.
Group | Treatment | % of inhibition |
---|---|---|
1 | Control (NC) | 0 |
2 | 1×10-7 | 9.9 |
3 | 3.33 × 10-7 | 12.5 |
4 | 1×10-6 | 5.4 |
5 | 3.33 × 10-6 | 16.4 |
6 | 1×10-5 | 13.8 |
7 | 3.33 × 10-5 | 63.4 |
8 | 1×10-4 | 63.4 |
9 | 3.33 × 10-4 | 94.4 |
10 | 1×10-3 | 91.7 |
11 | 3.33×10-3 | 85.5 |
The cells in each group were treated with 4-OH-TAM at the indicated concentrations for 72 h. The cell viability in each group was determined by CCK8 assay with commercial CCK8 kit.