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. 2017 Dec 20;9(2):2591–2602. doi: 10.18632/oncotarget.23515

Figure 5. MELK inhibitor OTSSP167 exhibits inhibitory effects in NB.

Figure 5

(A) The effects of OTSSP167 on anchorage-independent colony formation and growth in soft agar assay were shown. (B) Number counts of (A). (C) The effects of OTSSP167 on p-Rb level in NB cells were shown by immunoblotting assay. The anti-β-actin antibody was used as a loading control for whole cell extracts. (D) The effects of OTSSP167 on NB cell cycle by flow cytometry analysis.