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. 2017 Dec 21;9(2):2646–2659. doi: 10.18632/oncotarget.23522

Figure 6. RUNX2 promotes the burn wound healing of mice.

Figure 6

(A) Degree II burn wound were created on the back of mice. ADSCs stably expressing RUNX2 or shRUNX2 were injected into the burn wounds. Gross appearance of the skin wounds were evaluated 7 days after treatment. (B) ADSCs marked with fluorescent dye CM-Dil were injected into the burn wounds, red fluorescence indicates CM-Dil-labeled ADSCs nuclei. The distribution of CM-Dil-labeled cells was observed 7 days after seeded in wound (×200). (C) HE staining were employed to evaluate the dermal collagen levels, fibroblast numbers and capillary density of burn wounds (×200). Data were shown as means ±SD (*P<0.05, **P<0.01, ***P<0.001).