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. 2017 Dec 23;9(2):2678–2696. doi: 10.18632/oncotarget.23626

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Copyright: © 2018 More et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Topology map of differentially expressed metabolites generated using metaboanalyst describing the impact of metabolites identified through comparative analysis of IDC against control. Top pathways identified in tissue are 1. Nitrogen metabolism, 2. Pyrimidine metabolism, 3. Aminoacyl-tRNA biosynthesis, 4. Fatty acid biosynthesis, 5. D-Glutamine and D-glutamate metabolism, 6. Riboflavin metabolism, 7. Purine metabolism, 8. Alanine, aspartate and glutamate metabolism, 9. Phenylalanine, tyrosine and tryptophan biosynthesis, 10. Beta-Alanine metabolism.