In vivo |
Localizing target molecules inside a living cell |
[90] |
Cell-based |
Targeting the whole live cell |
[91] |
One-round step |
One selection rounds of aptamer generation |
[92] |
In silico |
Computational docking technology |
[93] |
Capillary electrophoresis |
Electrophoretic mobility based separation |
[94] |
Magnetic bead-based |
Magnetic beads immobilization |
[95] |
High-throughput sequencing-based |
High-throughput sequencing and bioinformatics analysis |
[96] |
Ligand-guided selection |
Using specific antibody to compete with the target molecule |
[97] |
Isogenic cell |
Isogenic cell line application in counter selection step |
[98] |
Quantitative parallel aptamer selection system |
Combination of microfluidic, next generation sequencing, and in situ-synthesized arrays |
[99] |