Figure 6.

Telomeres

(A) Spermatocyte chromosome spreads of Smc1β^+/+, Smc1β^−/−, and Smc1β^−/−,1a mice, stained with anti-SYCP3 (green) for AEs/LEs and with telomere FISH probe (red).

(B–D) Spermatocyte chromosome spreads of Smc1β^+/+, Smc1β^−/−, and Smc1β^−/−,1a mice, stained with anti-SYCP3 (red) for AEs/LEs and for telomeres with anti-RAP1 (green; B), anti-SUN1 (green; C), and anti-TRF2 (green; D). Yellow arrow indicates fused telomeres, blue arrow indicates chromosome ends without telomere, and white arrow indicates telomere stretches (scale bar, 5 μm).

See also Figures S6 and S7.