Table 4.
Summary for the identification of abnormalities in the sudden intrauterine unexplained death syndrome.
| Reference | Year | Methods | Tested sample | Results |
|---|---|---|---|---|
| (50) | 2014 | Fetal growth restriction (FGR) | Rats, guinea pigs, rabbits, and sheep | FGR is related with minimizing brain volume and altered structure, cortical volume, and decreased total myelination that deficits cells number |
| (51) | 2014 | Magnetic resonance imaging (MRI), corpus callosum, and intrauterine growth-restricted (IUGR) fetuses | 173 IUGR fetuses | Further explored corpus callosum to predict anomalous neurodevelopment risk in pregnancies |
| (52) | 2014 | NRG1-IVNV | 41 cases | Development of human neocortical provides expression of quantitative NRG1 isoform |
| (53) | 2017 | Cerebral palsy | Therapeutic candidates | Injury to developing the brain caused by the cerebral palsy |
| (54) | 2017 | Perinatal hypoxia | Humans and animals | In the FGR hypoxia is a vital problem in fetal–maternal medicine |
| (55) | 2017 | Human amnion epithelial cells (hAECs) | Mouse model | hAECs release trophic factors |
| (56) | 2003 | Diagnosis of IUGR, respiratory distress syndrome, intraventricular hemorrhage, and necrotizing enterocolitis | Newborn infants | Increased IUGR with prematurity and represent a vital risk factor in women when present with labor preterm |
| (57) | 2015 | Ultrasound appearance of brain volume and cortical development in fetuses | 20 fetuses | Brain volume smaller in IUGR fetuses, with accelerated or normal cortical maturation as depicted with the examination of postnatal MRI, can be described by 3D prenatal ultrasound |
| (58) | 2015 | HbF and BCL11A | 3 patients | It highlights the significance of using hematopoietic-specific methods when trying to target therapeutically BCL11A |