FIG 10.

GFZF binds the promoter region of male-specific lethal (MSL) complex genes. UCSC Genome browser shots of genes encoding components of the MSL complex are shown. GFZF's appearance in a screen for hybrid inviability, which leads to male lethality, could pertain to its role in expression of components of the MSL complex. Shown are forward (+)- and reverse (−)-strand ChIP-exo reads for M1BP, GFZF, or a no-IgG ChIP control. Bars in black show the genomic location of MultiGPS-generated peaks for either GFZF or M1BP.