FIG 9.

GFZF binds the promoters of genes involved in the G-to-M DNA damage checkpoint. Based on an RNAi screen, Myt1, 14-3-3ε, and tefu were among the top genes to affect the G₂-to-M DNA damage checkpoint (10). UCSC Genome browser shots of ChIP-exo data show that GFZF associates with the promoters of all three genes. Shown are forward (+)- and reverse (−)-strand ChIP-exo reads for M1BP, GFZF, or a no-IgG ChIP control. Bars in black show the genomic location of MultiGPS-generated peaks for either GFZF or M1BP.