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. 2018 Jan 29;8:1812. doi: 10.1038/s41598-018-20220-8

Table 3.

Sample demographics and TEG results for both WB and PPP before and after exposure to TNF-α or C3. Values presented as median ± standard deviation.

Demographic Data of Healthy Individuals N = 14; Age 24.0 ± 12.2; M = 57%; F = 43%
TEG results for naïve whole blood exposed to TNF-α or C3 for 10 minutes at room temperature
Naïve (n = 8) TNF-α (n = 8) Naïve vs TNF-α P-value Complement 3 (n = 8) Naïve vs C3 P-value
R 9.30 ± 1.47 8.40 ± 1.09 0.077 8.85 ± 0.93 <0.0001
K 3.80 ± 0.95 3.45 ± 1.02 0.16 3.55 ± 1.04 0.24
Angle 45.10 ± 5.37 48.50 ± 7.57 0.16 47.20 ± 7.66 0.16
MA 52.25 ± 5.43 54.35 ± 8.03 0.96 53.30 ± 5.32 0.76
MRTG 3.35 ± 0.79 3.82 ± 1.03 0.17 3.89 ± 1.06 0.17
TMRTG 13.84 ± 3.49 12.54 ± 3.66 0.37 13.17 ± 2.46 0.45
TTG 547.03 ± 141.48 596.87 ± 150.22 0.86 594.38 ± 127.38 0.77
TEG results for naïve platelet poor plasma exposed to TNF-α or C3 for 10 minutes at room temperature
Naïve (n = 11) TNF-α (n = 11) Naïve vs TNF-α P-value Complement 3 (n = 11) Naïve vs C3 P-value
R 13.20 ± 3.31 11.80 ± 1.97 0.03 10.60 ± 2.58 0.03
K 4.50 ± 2.31 4.60 ± 1.31 0.60 4.80 ± 2.17 0.94
Angle 43.60 ± 13.73 47.80 ± 8.55 0.11 52.00 ± 10.00 0.12
MA 23.80 ± 5.51 24.60 ± 4.92 0.99 22.90 ± 6.32 0.91
MRTG 3.11 ± 1.35 3.16 ± 1.62 0.05 3.41 ± 1.75 0.03
TMRTG 13.92 ± 3.51 13.33 ± 2.33 0.02 11.83 ± 3.18 0.13
TTG 155.64 ± 56.98 164.16 ± 54.24 0.83 148.62 ± 64.15 0.83