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Micrographs obtained after immunohistochemistry test on cell suspensions of (A) SKOV-3 cells (HER-2-positive) and (B) MDA-MB-468 cells (HER-2-negative) to compare the presence of HER-2 receptors; and (C) micrographs of SKOV-3 tumor tissue, indicating the presence of HER-2 receptors on cell membrane (considered as 3+ score), defined as strong complete membrane staining in more than 30% of tumor cells.
