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. 2018 Jan 23;10:21–34. doi: 10.2147/NSS.S124657

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© 2018 Osman et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Schematic of the anatomical and non-anatomical causes of OSA.

Notes: Some degree of anatomical vulnerability is present in OSA. However, the extent of impairment varies widely between patients. The non-anatomical contributors, which are present in approximately 70% of OSA patients, play a key role in mediating the absence or presence of OSA. In the schematic, the gray tracings indicate the desired response, whereas the black tracings represent impairment in the non-anatomical trait. Refer to the text for further detail. Reprinted from Chest, Carberry JC, Amatoury J, Eckert DJ, Personalized management approach for OSA, Epub 2017 June 16, Copyright (2017), with permission from Elsevier.36

Abbreviations: EEG, electroencephalography; EMG, genioglossus electromyography; MTA, 100 ms moving time average of the rectified raw EMG signal; OSA, obstructive sleep apnea.