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. 2018 Jan 28;11(2):250–258. doi: 10.1016/j.tranon.2018.01.001

Figure 4.

Figure 4

Expression of PD-L1 in tumor tissues of orthotopic HCC mice. Sorafenib was administered for 21 days in mice with orthotopic HCC and 7 days after treatment, the tumor issues were collected. A. Representative images of immunohistochemical staining of PD-L1 in the PBS and sorafenib treatment groups. B. Representative images of PD-L1 by Western blotting in the PBS and sorafenib treatment groups. C. qRT-PCR assay for PD-L1 mRNA expression in tumor tissue from the PBS and sorafenib treatment groups (n = 6 mice/group, **P < .01).