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. 2018 Jan 20;7(1):19. doi: 10.3390/antiox7010019

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Illustration of the top networks identified by Ingenuity Pathway Analysis for the response to senescence (A) and selenium level variation (B). ACTA1: Actin, alpha skeletal muscle; ACTG1: Actin, cytoplasmic 2; ALDH2: Aldehyde dehydrogenase, mitochondrial; aldo: aldolase; ANXA1: Annexin A1; ANXA4: Annexin A4; ANXA5: Annexin A5; APA: Aminopeptidase A; Arp2/3: Actin-related protein 2/3; ARPC2: Actin-related protein 2/3 complex subunit 2; ARPC5: Actin-related protein 2/3 complex subunit 5; ARPC5L: Actin-related protein 2/3 complex subunit 5-like protein; BLVRA: Biliverdin reductase A; CASP8AP2: Caspase-8-associated protein 2; CAT: Catalase; CTSD: Cathepsin D; DES: Desmin; ERK1/2: Extracellular signal-regulated kinase 1/2; ERP29: Endoplasmic reticulum resident protein 29; FDXR: Ferredoxin reductase; G6PD: Glucose-6-phosphate 1-dehydrogenase; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; GNB2L1: Guanine nucleotide-binding protein subunit beta-2-like 1; GSTP1: Glutathione S-transferase P; hCG: Human chorionic gonadotropin; HSP: Heat shock protein; HSP27: Heat shock protein beta-1; HSPB1: Heat shock protein beta-1; HSPB6: Heat shock protein beta-6; LDL: Beta Lipoprotein; Lh: Light-harvesting complex; LMNA: Prelamin-A/C; Nfat: Nuclear factor of activated T-cells; NKkB: Nuclear factor NF-kappa-B; P38 MAPK: Mitogen-activated protein kinase 14; P4HB: Protein disulfide-isomerase; PBH: Prohibitin; PGAM1: Phosphoglycerate mutase 1; PHB2: Prohibitin-2; pkg: protein KINASE G; PLA2: Phospholipases A2; PRDX2: Peroxiredoxin-2; PRDX6: Peroxiredoxin-6; SET: Protein SET; SOD1: Superoxide dismutase [Cu-Zn]; SOD2: Superoxide dismutase [Mn], mitochondrial; TALDO1: Transaldolase; TUBB: Tubulin beta chain; TUBB4B: Tubulin beta-4B chain; VIM: Vimentin.

Illustration of the top networks identified by Ingenuity Pathway Analysis for the response to senescence (A) and selenium level variation (B). ACTA1: Actin, alpha skeletal muscle; ACTG1: Actin, cytoplasmic 2; ALDH2: Aldehyde dehydrogenase, mitochondrial; aldo: aldolase; ANXA1: Annexin A1; ANXA4: Annexin A4; ANXA5: Annexin A5; APA: Aminopeptidase A; Arp2/3: Actin-related protein 2/3; ARPC2: Actin-related protein 2/3 complex subunit 2; ARPC5: Actin-related protein 2/3 complex subunit 5; ARPC5L: Actin-related protein 2/3 complex subunit 5-like protein; BLVRA: Biliverdin reductase A; CASP8AP2: Caspase-8-associated protein 2; CAT: Catalase; CTSD: Cathepsin D; DES: Desmin; ERK1/2: Extracellular signal-regulated kinase 1/2; ERP29: Endoplasmic reticulum resident protein 29; FDXR: Ferredoxin reductase; G6PD: Glucose-6-phosphate 1-dehydrogenase; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; GNB2L1: Guanine nucleotide-binding protein subunit beta-2-like 1; GSTP1: Glutathione S-transferase P; hCG: Human chorionic gonadotropin; HSP: Heat shock protein; HSP27: Heat shock protein beta-1; HSPB1: Heat shock protein beta-1; HSPB6: Heat shock protein beta-6; LDL: Beta Lipoprotein; Lh: Light-harvesting complex; LMNA: Prelamin-A/C; Nfat: Nuclear factor of activated T-cells; NKkB: Nuclear factor NF-kappa-B; P38 MAPK: Mitogen-activated protein kinase 14; P4HB: Protein disulfide-isomerase; PBH: Prohibitin; PGAM1: Phosphoglycerate mutase 1; PHB2: Prohibitin-2; pkg: protein KINASE G; PLA2: Phospholipases A2; PRDX2: Peroxiredoxin-2; PRDX6: Peroxiredoxin-6; SET: Protein SET; SOD1: Superoxide dismutase [Cu-Zn]; SOD2: Superoxide dismutase [Mn], mitochondrial; TALDO1: Transaldolase; TUBB: Tubulin beta chain; TUBB4B: Tubulin beta-4B chain; VIM: Vimentin.