Table 3.

Ingenuity Pathway Analysis of functional networks affected by selenium in young or senescent cells.

Network	Members	Molecules	Associated Groups or Molecules
Immune, inflammatory and hematologic diseases	21	ACTA1, ACTB, ACTG1, ALDH2, ANXA1, ANXA2, ANXA4, ANXA5, DES, FDXR, GADPH, LMNA, P4HB, PHB2, PPA1, RNH1, STRAP, TUBB, TUBB4B, VIM	Actin, alpha actin, alpha tubulin, Ap1, Beta tubulin, CD3, estrogen receptor, F actin, FSH, Insulin, Lh, NFkB (complex), Profilin, Rock
Cellular Function and Maintenance, energy production, lipid metabolism	12	ALDOA, BLVRA, CAT, FH, IDH1, MDH1, PEPD, PKM2, POTEE/POTEF, PSMD14, TRAP1, VPS13D	26S proteasome, Akt, BLVRB, ERK1/2, Histone H4, IL22R1-IL10R2, INPP4B, Jnk, Jun-GABP, LEMD2, Mapk, N-arachidonylglycine, NUDT6, P38 MAPK, Pkc(s), PSME4, S100A16, SBSN, SLC26A6, SPRED3, TBCE, UBC, Ybx1-ps3
Cancer, neurological disease and cell signaling	1	CEP104	NR2F6