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TBI induces apoptosis via caspase-3 in vivo: (A–C). Western blotting of cleaved caspase-3 (A), cleaved PARP (PARP p85) (B) and annexin V (C) in the brain cortex tissue lysates from uninjured control and FPI animals (7 psi and 15 psi) 9 days after injury. Values are mean ± SEM; n = 4. * p < 0.05, ** p < 0.01, *** p < 0.001 versus uninjured control; # p < 0.05; ## p < 0.01 versus 7 psi injury.
