Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 23;10(1):3. doi: 10.3390/cancers10010003

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Overview of inhibitors for targeting lipid metabolism in cancers (ACAT: acyl-CoA cholesterol acyltransferase; ACC: Acetyl-CoA carboxylase; ACLY: ATP-citrate lyase; ACSS: acyl-CoA synthetase short chain family member; AMPK: AMP-activated protein kinase; ALDH: Aldehyde dehydrogenase; CiC: citrate carrier; ER: endoplasmic reticulum; FA: fatty acid; FASN: fatty acid synthase; GLS: glutaminase; GLUD: glutamate dehydrogenase; GOT: aspartate transaminase; HIF: hypoxia inducible factor; HMG: 3-hydroxy-3-methylglutaryl-coenzyme A; IDH: isocitrate dehydrogenase; α-KG: α-ketoglutarate; LKB1: liver kinase B1; LDLR: low-density lipoprotein receptor; MCT: monocarboxylate transporter; MDH: malate dehydrogenase; ME: malate enzyme; SCD: ∆⁹-stearoyl-CoA desaturase; SLC: solute carrier; SREBP: sterol regulatory element-binding protein; TCA: tricarboxylic acid cycle).