Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 10;10(1):14. doi: 10.3390/cancers10010014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Epithelial/non-stem cell to mesenchymal/cancer stem cell plasticity. Epithelial/non-cancer stem cells retaining cell plasticity respond to environmental or intrinsic cues by fluidly transitioning through intermediary stages until reaching a mesenchymal/cancer stem cell state. These intermediary states hold immense plasticity and are the roots behind metastatic dissemination and therapeutic failure. CSC: cancer stem cell.