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. 2018 Feb 5;215(2):521–535. doi: 10.1084/jem.20170686

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© 2018 Sun et al.

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Figure 3. — γδ T cell–derived IFN-γ is critical in impairing recovery after SCI. (A–C) TCRδ^−/− SCI mice were reconstituted with γδ T cells from WT or IFN-γ^−/− animals or PBS alone, and evaluation of recovery after SCI. (D–F) Functional recovery of TCRδ^−/− SCI mice reconstituted with Vγ4 γδ T cells from WT or IFN-γ^−/− mice or PBS only. (G–I) Recovery after SCI of TCRδ^−/− SCI mice reconstituted with Vγ1 γδ T cells from WT or IFN-γ^−/− mice or PBS only. Error bars represent mean ± SEM. (A, D, and G) Two-way repeated measures ANOVA with Bonferroni’s post-hoc correction. (B, C, E, F, H, and I) One-way ANOVA with Tukey’s multiple comparisons test. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. n.s., not significant. n = 8.