THF cells were seeded in 12 well plate, and left mock treated or treated with serial of doses of DSDP or control compound G10 for 6 h. Total cellular RNAs were extracted to detect the mRNA of IFN-β (A), TNFα (B), IL-29 (C), and IL-6 (D) by qRT-PCR. Values represented fold of induction relative to mock treated control (mean ± standard deviation, n=4). * indicates p<0.05 compared to mock treated control.