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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Antiviral Res. 2017 Oct 2;147:37–46. doi: 10.1016/j.antiviral.2017.10.001

Figure 8. DSDP inhibited the replication of Yellow fever, Dengue and Zika viruses in THF cells.

Figure 8

THF cells were left untreated or treated with indicated concentrations of DSDP or control compound G10 for 8 h. Cells were then infected with YFV, DENV, or ZIKV at MOI of 0.1 for 1 h followed by culture for additional 48 h. Total cellular RNAs were extracted to detect viral genomic RNA by qRT-PCR using β-actin as internal control (A, C and E). Values represented percentage to mock treated controls (mean ±standard derivations, n=3). Culture media were harvested and the virus titers (B, D and F) were determined by plaque assay and presented as number of plaque forming units per milliliter medium (PFU/ml) (mean ±standard derivations, n=3). UD, under detection limit. * indicates p<0.05 compared to mock treated control.