Figure 9.
Model. Transcription initiation from the late promoter is increased in response to cellular differentiation signals through the activity of differentiation-specific transcription factors (TF-X) such as C/EBPβ (Bodily et al., 2006; Bodily and Meyers, 2005; Gunasekharan et al., 2012; Kukimoto and Kanda, 2001; Kukimoto et al., 2006; Spink and Laimins, 2005). E7 promoter transcription through activation of a specific transcription factor or coregulator (TF-Y), or through effects on the general transcription machinery.