Table 2.
Summary of diagnostic accuracy of assays for detection of anti-HIV antibodies, anti-HCV antibodies, and HCV-RNA using DBS samples.
| Screening test | TP | FP | TN | FN | Se (95%CI) |
Sp (95%CI) |
PPV (95%CI) |
NPV (95%CI) |
LR + (95%CI) | LR– (95%CI) |
|---|---|---|---|---|---|---|---|---|---|---|
| Anti-HIV antibodies | 40 | 0 | 99 | 0 | 100% (91.2%; 100%) |
100% (96.3%; 100%) |
100% (91.2%; 100%) |
100% (96.3%; 100%) |
N/A | N/A |
| Anti-HCV antibodies | 100 | 0 | 31 | 8 | 92.6% (86.1%; 96.2%) |
100% (89%; 100%) |
100% (96.3%; 100%) |
79.5% (64.5%; 89.2%) |
N/A | 0.07 (0.04; 0.14) |
| HCV-RNA | 107 | 0 | 31 | 1 | 99.1% (94.9%; 99.8%) |
100% (89%; 100%) |
100% (96.5%; 100%) |
96.9% (84.3%; 99.4%) |
N/A | 0.01 (0.00; 0.07) |
Abbreviations: FN, false negative; FP, false positive; TN, true negative; TP, true positive; LR+, positive likelihood ratio; N/A, not available LR−, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; Se, sensitivity; Sp, specificity.