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Migraine patients have lower neocortical 5-HT4 receptor binding than controls (0.60 ± 0.09 vs. 0.67 ± 0.05, p = .024) after adjusting for covariates (5-HTTLPR status, age, and sex). Black bars indicate mean ± SD. The difference remained after exclusion of subject 15 (the patient with the lowest BPND) (0.63 ± 0.06 vs. 0.68 ± 0.05, p = .038).
