Table 1.
Demographics of study population.
| Uninfected (N = 17) | Infected (N = 16) | Septic (N = 17) | Healthy (N = 12) | ||
|---|---|---|---|---|---|
| Age | 43.1 ± 11.5 | 40.4 ± 12.1 | 47.3 ± 10.7 | 29.2 ± 3.8 | |
| Male (%) | 9 (53) | 10 (63) | 11 (65) | 10 (83) | |
| Female (%) | 8 (47) | 6 (37) | 6 (35) | 2 (17) | |
| APACHE II scores | 4 ± 2 | 9 ± 1 | 15 ± 3 | 0 | |
| SOFA scores | 0.06 ± 0.24 | 0.44 ± 0.11 | 6.47 ± 3.45 | 0 | |
| Lac (mmol/L) | 1.3 ± 0.5 | 1.2 ± 0.5 | 2.4 ± 2.7 | N/A | |
| C-reactive protein (mg/L) | 59.5 ± 37.1 | 133.4 ± 77.3 | 196.1 ± 71.2 | N/A | |
| Hematologic analysis | White blood cell count (×109/L) | 8.7 ± 2.5 | 12.8 ± 7.5 | 16.9 ± 14.6 | 6.7 ± 1.1 |
| Neutrophil percentage (%) | 76.3 ± 7.3 | 83.3 ± 6.3 | 86.4 ± 8.2 | 62.4 ± 10.1 | |
| Lymphocyte percentage (%) | 14.0 ± 5.5 | 9.8 ± 5.1 | 7.8 ± 5.0 | 27.8 ± 9.4 | |
| Hematocrit | 0.30 ± 0.039 | 0.27 ± 0.045 | 0.28 ± 0.059 | 0.43 ± 0.030 | |
| Platelet (×109/L) | 276 ± 86 | 207 ± 92 | 186 ± 139 | 257 ± 70.9 | |
| Liver function | Total protein (g/L) | 55.7 ± 6.6 | 54.1 ± 6.9 | 51.6 ± 6.2 | 74.1 ± 4.9 |
| Albumin (g/L) | 32.8 ± 3.4 | 30.9 ± 3.3 | 29.6 ± 2.8 | 47.1 ± 2.2 | |
| Total bilirubin (μmol/L) | 9.8 ± 5.1 | 16.4 ± 17.2 | 40.5 ± 8.7 | 11.9 ± 2.8 | |
| Direct bilirubin (μmol/L) | 5.0 ± 2.6 | 9.5 ± 14.0 | 29.9 ± 9.0 | 4.1 ± 1.2 | |
| Indirect bilirubin (μmol/L) | 4.8 ± 2.8 | 6.9 ± 4.3 | 10.6 ± 6.8 | 7.8 ± 1.9 | |
| Renal function | Creatinine (μmol/L) | 58 ± 50 | 103 ± 133 | 136 ± 120 | 72 ± 21 |
| Urea N (mmol/L) | 7.4 ± 12.1 | 6.1 ± 5.0 | 8.9 ± 7.0 | 5.8 ± 1.4 | |
| Uric acid (μmol/L) | 203 ± 105 | 166 ± 95 | 219 ± 134 | 299 ± 110 | |
| Blood coagulation | Prothrombin time (s) | 13.0 ± 0.9 | 15.6 ± 6.1 | 16.4 ± 4.6 | 12.4 ± 1.0 |
| Partial thromboplastin time (s) | 37.3 ± 7.2 | 53.9 ± 31.3 | 59.6 ± 28.9 | 28.8 ± 2.3 | |
| International normalized ratio | 1.14 ± 0.080 | 1.36 ± 0.54 | 1.43 ± 0.41 | 1.08 ± 0.089 | |
| Fibrinogen (mg/dL) | 4.44 ± 0.81 | 4.21 ± 1.18 | 4.10 ± 1.09 | 2.63 ± 0.64 | |
| Infection | Microbiologically confirmed (%) | 0 | 25.0 | 35.3 | 0 |
| Clinically proven or suspected (%) | 0 | 100.0 | 100.0 | 0 | |
| Type of organisms | Gram-positive (%) | 0 | 6.3 | 5.9 | 0 |
| Gram-negative (%) | 0 | 18.7 | 23.5 | 0 | |
| Fungus (%) | 0 | 0 | 5.9 | 0 |
N/A, no available.