Table 1.

Demographic, operative, and clinical data of younger and elderly patients undergoing hepatectomy and pancreaticoduodenectomy

Variables	Elderly (≥70 years) (n=111)	Younger (<70 years) (n=901)	p-value
Gender, male	81 (73.0%)	619 (68.7%)	0.358
Body mass index	23.5±3.6	22.8±3.2	0.215
Child–Pugh class			0.001
A	61 (55.0%)	642 (71.3%)
B	50 (45.0%)	259 (28.7%)
Smoking history	36 (32.4%)	347 (38.5%)	0.215
Diabetes	18 (16.2%)	76 (8.4%)	0.014
Cardiovascular disease	44 (39.6%)	128 (14.2%)	<0.001
ASA score			0.001
I	5 (4.5%)	29 (3.2%)
II	68 (61.3%)	696 (77.2%)
III	38 (34.2%)	176 (19.5%)
Hepatitis B and/or C	19 (17.1%)	423 (46.9%)	<0.001
Alanine aminotransferase (U/L)	97.9±114.8	91.6±129.8	0.623
Aspartate aminotransferase (U/L)	92.0±90.6	82.2±104.7	0.342
Total bilirubin (µmol/L)	105.1±125.7	65.9±107.4	0.003
Albumin (g/L)	36.8±6.5	38.4±5.2	0.003
White blood cells (×109/L)	6.5±2.6	6.0±2.7	0.029
Hemoglobin (g/L)	122.3±17.6	128.8±19.4	0.001
Platelet (×109/L)	179.5±66.3	173.3±85.9	0.112
Operation time (min)	268±64	261±83	0.082
Blood loss (mL)	541.9±459.4	678.9±751.1	0.061
Intraoperative transfusion	46 (41.4%)	413 (45.8%)	0.419
Pathological diagnosis
Liver disease			0.166
Hepatocellular carcinoma	37 (33.3%)	479 (53.2%)
Intrahepatic cholangiocarcinoma	8 (7.2%)	50 (5.5%)
Metastatic tumors	4 (3.6%)	32 (3.6%)
Pancreas disease			0.656
Adenocarcinoma	58 (52.3%)	295 (32.7%)
Benign/borderline tumors	4 (3.6%)	45 (5.0%)
Surgical procedures			<0.001
Hepatectomy	49 (44.1%)	561 (62.3%)
Pancreaticoduodenectomy	62 (55.9%)	340 (37.7%)
Types of hepatectomy			0.818
Major hepatectomy	15 (30.6%)	163 (29.1%)
Minor hepatectomy	34 (69.4%)	398 (70.9%)
Vascular resection	4 (3.6%)	60 (6.7%)	0.298

Note: Continuous variables are expressed as mean ± SD and categorical variables as number (percentage).

Abbreviation: ASA, American Society of Anesthesiologists.