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DNA-binding ability of AEMA-g-WSC. (A) DNA-mobility assay results for AEMA, WSC, and AEMA-g-WSC at various weight ratios. (B) Sizes and zeta potentials of pDNA complexes. (C) Electron micrographs observed under TEM. (1) native pDNA. (2) pDNA/WSC at a w/w ratio of 1:4. (3) pDNA/AEMA-g-WSC nanoparticles at a w/w ratio of 1:4.
Abbreviations: AEMA, 2-aminoethl methacrylate; AEMA-g-WSC, 2-aminoethl methacrylate-grafted water-soluble chitosan; WSC, water-soluble chitosan.
