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Pedigree demonstrating familial aggregation of HS. Three cases, 2 dogs with confirmed HS included in the study and 1 additional dog with presumptive HS (lung mass with histiocytic proliferation), were discovered to be full siblings from separate litters. A fourth confirmed HS case was related to these dogs through a recent common ancestor. Solid, histiocytic sarcoma; Lines, histiocytic proliferation; Dots, common ancestor
