Table 4.
Summary of randomized controlled trials’ adverse events using aerobic MICT versus HIIT for patients with coronary artery disease
| RCT study | Cardiac adverse events reported HIIT | Cardiac adverse events reported MICT | Other adverse events HIIT | Other adverse events MICT | Events recorded but not classified by intensity |
|---|---|---|---|---|---|
| Jensen et al31 | Events not reported | Events not reported | Events not reported | Events not reported | Events not reported |
| Rognmo et al32 | Nil events | Nil events | 1 ankle fracture | 1 knee injury | Nil events |
| Warburton et al33 | Nil events | Nil events | Nil events | Nil events | Nil events |
| Amundsen et al34 | Nil events | Nil events | Nil events | Nil events | Physical impairment not related to cardiovascular disease |
| Moholdt et al35 | Nil events | Nil events | Leg pain, hip pain, bronchitis | Readmitted to hospital (reason not reported), pericardial effusion | Nil events |
| Benetti et al36 | Nil events | Nil events | Nil events | Nil events | Unstable angina ×2 joint problems |
| Moholdt et al37 | Angina caused drop out | Angina caused drop out | Gastroenteritis, pancreatitis, intermittent claudication | Gastrointestinal bleeds, bronchitis, knee surgery, low back pain, psychiatric disease | Nil events |
| Rocco et al38 | Events not reported | Events not reported | Events not reported | Events not reported | Events not reported |
| Currie et al39 | Nil events | Nil events | Nil events | 1× musculoskeletal injury unrelated to training caused inability to perform post-training test | Nil event |
| Keteyian et al40 | Nil events | Nil events | Knee pain ×1 requiring 2-week rest | 1× limiting leg pain | Nil events |
| Cardozo et al41 | Nil events | Nil events | Nil events | Nil events | Nil events |
| Conraads et al42 | Nil events | Nil events during training 1 acute M1 requiring PCI greater than 24 hours post training. Two episodes of significant ST depression was seen on exercise testing 6 weeks post training. Both required PCI. |
Nil events | Nil events | Nil events |
| Currie et al43 | Events not reported | Events not reported | Events not reported | Events not reported | Events not reported |
| Kim et al44 | Nil events | Nil events | Nil events | Nil events | Nil events |
| Jaureguizar et al45 | Nil events | Nil events | Nil events | Nil events | Nil events |
| Möbius-Winkler et al46 | Nil events | Nil events | Nil events | Nil events | Progression of CAD ×1 after 4 weeks training and increased angina requiring PCI |
| Prado et al47 | Events not reported | Events not reported | Events not reported | Events not reported | Events not reported |