Table 3.
The mechanisms through which miRNAs induce chemoresistance
| miRNA | Mechanisms | Reference |
|---|---|---|
| miR-let-7 | E2F2, c-Myc, KRAS, and MAPK | 70 |
| miR-10b | RAS, Tiam1, HOXD10, and KLF4 | 71 |
| miR-21 | EGFR, HER2/neu, PDCD4, BCL2, PTEN, TIMP2, and TIMP3 | 73, 74 |
| miR-29a | Dkk1, Kremen2, sFRP2, and Wnt/beta-catenin signaling pathway | 78 |
| miR-34 | BCL-2 | 66 |
| miR-99b | mTOR | 80 |
| miR-101-3p | RRM1 | 80 |
| miR-125b | BAP1, BBC3, NEU1, BCL2, and STARD13 | 81 |
| miR-155 | SMG-1 | 83 |
| miR-181b | NF-kappaB and CYLD | 85 |
| miR-200 | ZEB1, slug, and vimentin | 70 |
| miR-204 | MIC-1 | 82 |
| miR-210 | ABCC5 | 86 |
| miR-214 | PTEN and ING4 | 87 |
| miR-221 | IRAK3, C5ORF41, KLF12, and MAPK10 | 72 |
| miR-320a | PDCD4 | 88 |
| miR-320c | SMARCC1 | 89 |
| miR-365 | SHC1 and BAX | 67 |
| miR-1246 | CCNG2 | 68 |