Table 1. Tissues with detectable ZIKV RNA from mother and fetus.
| Tissue Source | Organ System | Tissue Name | vRNA copies/mg |
|---|---|---|---|
| Maternal | Immune | Axillary LN | 258.3 |
| Inguinal LN | 1774.8 | ||
| Mesenteric LN | 9763.8 | ||
| Spleen | 981.9 | ||
| Pelvic LN | 583.7 | ||
| Reproductive | Decidua basalis | 278.2 | |
| Uterus | 1471.7 | ||
| Uterus/placental bed | 486.5 | ||
| Fetal | Digestive System | Stomach | 6140.4 |
| Colon | 355157.0 | ||
| Jejunum | 2055.9 | ||
| Liver | 5.4 | ||
| Renal | Kidneys | 51.1 | |
| Urinary Bladder | 185.1 | ||
| Cardiovascular | Aorta-thoracic | 921.3 | |
| Heart | 366.0 | ||
| Pericardium | 1196.3 | ||
| Extraembryonic | Amniotic Chorionic Membrane | 4933.7 | |
| Placental Disc 1 | 64.4 | ||
| Umbilical Cord | 6.0 | ||
| Connective | Adipose Tissue-Omentum | 5102.2 | |
| Immune | Axillary LN | 287.6 | |
| Spleen | 261.1 | ||
| Thymus | 215.3 | ||
| Musculoskeletal | Muscle-quadriceps | 387.0 | |
| Pulmonary | Lung | 37947.0 | |
| Reproductive | Sem vesicle/Prostate | 5700.0 | |
| Testis | 5188.1 | ||
| Central Nervous | Cerebrum 3 right* | 72.9 | |
| Dura Mater | 74.3 | ||
| Ocular | Cornea | 135.1 | |
| Retina | 316.5 | ||
| Sclera | 370.8 |
127 maternal biopsies and fetal tissues were assayed for vRNA. All the tissues positive for ZIKV RNA are listed in this table. The maternal and fetal tissues which were vRNA negative are listed in S1 Table.
*Serial brain sections were performed, rather than specific dissection of brain structures, because of generalized autolysis.