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. 2018 Jan 30;13(1):e0191774. doi: 10.1371/journal.pone.0191774

Table 4. Stimulation parameters, medication quantification scales and analgesic effects per patient.

Diagnosis Groupa Pain relief, %, after
3 years of MCS
Level of pain controlb Intensity, Vc Frequency, Hzc Pulse width, μsc MQSpre MQSpost Changes in MQSd QLI pre QLI post Changes in QLIe
1 PSP A 54 2 2 50 90 16.5 4.2 Diminished N/A N/A N/A
2 PSP A 56 2 1.5 50 80 5.4 5.4 No change N/A N/A N/A
3 PSP A 60 2 2.5 50 60 15.3 13.2 Diminished 9 7 Diminished
4 PSP A 70 1 2.5 60 60 6.3 4.2 Diminished 14 2 Diminished
5 TN1 A 100 1 3 50 60 8.2 0 Diminished 7 2 Diminished
6 TN1 A 67 2 4.5 40 90 0 0 No change 14 4 Diminished
7 TN2 A 60 2 4.5 50 120 6.3 4.8 Diminished 8 4 Diminished
8 PSP B 20 3 2.5 50 90 26.1 4.2 Diminished 7 1 Diminished
9 PSP B 38 3 3 50 60 14.1 4.2 Diminished 11 10 Diminished
10 PSP B 20 3 2.5 50 60 0 5.4 Increased 16 16 No change
11 PIFP B 20 3 4 50 60 11.5 8.4 Diminished 16 12 Diminished
12 PIFP B 25 3 5 50 90 6.3 6.9 Increased 13 13 No change
13 CPSP B 25 3 3 50 60 6.4 7.8 Increased 16 8 Diminished
14 TNP B 0 3 3 40 60 6.8 10.7 Increased 12 10 Diminished
15 TNP B 10 3 2 40 80 23.4 15.6 Diminished 11 10 Diminished
16 BMS B 11 3 3 40 90 5. 5.4 No change 8 8 No change
17 PhP B 12.5 3 2.5 50 60 6.3 12 Increased N/A N/A N/A
18 AvP B 30 3 3 50 60 24.6 14.2 Diminished 17 8 Diminished

a Group A, responding patients; group B, non-responding patients

b Level 1, 70–100%; level 2, 40–69%; level 3, 0–39%.

c Stimulation parameters that were reported at the last follow-up.

d Dimished, MQS after MCS<MQS before MCS (negative rank); Increased, MQS after MCS>MQS before MCS (positive rank); No change, MQS after MCS equal to MQS before MCS (tie).

e Dimished, QLI after MCS<QLI before MCS (negative rank); Increased, QLI after MCS>QLI before MCS (positive rank); No change, QLI after MCS equal to QLI before MCS (tie).

AvP, avulsion pain; BMS, burning mouth syndrome; BPAP, brachial plexus avulsion pain; CPSP: Chronic post surgical pain; Hz, Hertz; μs, microseconds; MCS, motor cortex stimulation; MQS, medication quantification scale; MQSpost, medication quantification scale following MCS; MQSpre, medication quantification scale before MCS; N/A, Not available; PIFP, persistent idiopathic facial pain; PSP, post-stroke pain; QoL-index pre, Quality of life index before MCS; QoL-index post, Quality of life index following MCS; TN1, trigeminal neuralgia type 1 (>50% episodic); TN1, trigeminal neuralgia type 1 (>50% constant); TNP, trigeminal neuropathic pain