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. 2018 Jan 18;12(1):e0006160. doi: 10.1371/journal.pntd.0006160

Fig 1. Alignment of LieIF with its homologs eIF4AIhu (DDX2A), eIF4AIIIhu (DDX48), eIF4Ayeast and a more distantly related DBP involved in RNA transport DDX19Bhu (Δ:1-60).

Fig 1

Residues constituting pocket P1 are marked with red stars and those constituting P2 are marked with blue stars. Conserved motifs are indicated on top of the LieIF sequence. Domain 1 contains motifs Q [F–FxxPTxIQ], I [AxxGxGKT], Ia [PTRELA], GG [GG], Ib [TPGRx], II [DEAD] and III [SAT]. Domain 2, contains motifs IV [IIFxpppp] (where “p” denotes polar/charged residues), QxxR, V [TDxxARGxD] and VI [HRxGRxxR].