Fig 5. Interaction diagrams of compounds 6-α-aminocholestanol (20), 6-β-aminocholestanol and 6-ketocholestanol (48) (from left to right) with pocket P2 on apo-LieIF, in the non-phosphorylated form.

Hydrogen bonds are shown in green dashed lines along with their length in Å. Residues establishing hydrophobic interactions with the ligands atoms are shown in red incomplete circles. Ligand atoms of the compound that are implicated in these hydrophobic interactions are also surrounded by red sticks.