Table 1. Templates used to build the 3D models of LieIF (PDB ID and chain ID) listed with descending identity rates.

N°	PDB_ID	Fragment	Function	Organism	Resolution(Å)	Identity(%)
1	1FUK_A	230–394	Yeast eIF4A	Saccharomyces cerevisiae	1.75	57.69
2	3FHO_B	1–503	RNA helicase DBP5	Schizosaccharomyces pombe	2.80	40.07
3	2KBE_A	71–296	RNA helicase DBP5	Saccharomyces cerevisiae	NA(*)	39.55
4	1HV8_B	1–367	MjDEAD RNA helicase	Methanocaldococcus jannaschii	3.00	36.29
5	1XTI_A	46–428	RNA helicase P47	Homo sapiens	1.95	34.68
6	2JGN_C	408–579	RNA helicase DDX3X	Homo sapiens	1.91	34.39
7	1Q0U_B	2–219	BSTDEAD N-terminus	Geobacillus stearothermophilus	1.85	34.34
8	2Z0M_A	1–337	Hyp. RNA helicase	Sulfolobus tokodaii	1.90	31.50
9	3EAQ_B	215–426	RNA-dependant ATPase	Thermus thermophilus	2.30	28.93
10	3I32_A	218–517	RNA-dependant ATPase	Thermus thermophilus	2.80	27.27
11	2XB2_X	1–411	eIF4A-III (DDX48)	Homo sapiens	3.40	56.99
12	2HYI_I	1–411	Prob. RNA helicase DDX48	Homo sapiens	2.30	56.70
13	2GXQ_A	1–207	RNA-dependent ATPase	Thermus thermophilus	1.20	37.93
14	3FMO_B	1–300	RNA helicase DDX19B	Homo sapiens	2.51	37.33
15	2DB3_D	200–623	RNA helicase VASA	Drosophilia melanogaster	2.20	27.74
16	3DKP_A	139–381	Prob. RNA helicase DDX52	Homo sapiens	2.10	27.35
17	3I5X_A	37–597	RNA helicase MSS116	Saccharomyces cerevisiae	1.90	26.56

From 1-10: templates used to build apo-LieIF. Mean identity rate value is 36.5 ± 8.1%.

(*) NMR experiment.

From 11-17: templates used to build holo-LieIF. Mean identity rate value is 38.7 ± 12.3%.