Figure 5.
NK cells and CCL3 support inflammation and T cell homing. Mice were injected with 1 × 106 WTTU or L3TU cells in the left flank. At day 21, tumors were analyzed by qPCR for TGFβ, IL-10, TNF-α, IFNγ, CXCL9, and CXCL10. A, Relative change in cytokine expression in WTTU mass with or without NK cell depletion. B, Relative change in cytokine expression in L3TU tumor mass with or without NK cell depletion. C, Relative changes in cytokine production by L3TU and WTTU with NK cell depletion. Each symbol represents an individual animal.