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. 2017 Dec 8;19(2):105–112. doi: 10.1080/15384047.2017.1395116

Figure 5.

Figure 5.

Correlations between TGF-β signaling and clinicopathological characteristics. A. The levels of SMAD4 associated with N stage, TNM stage, and age (years) in cancer tissues. B. The levels of p-SMAD1/5/9 were increased in CRC patients with tumor volume ≤ 5 cm than those whom tumor volume > 5cm in cancer tissues. C. In stroma, the levels of p-SMAD1/5/9 were increased in CRC patients with tumor volume ≤ 5 cm than those whom tumor volume > 5 cm. D. In normal tissues, TGFBRII was correlated with tumor volume. E. p-SMAD1/5/9 was associated with differentiation in normal tissues. H, High; M, Moderate; L, Low.