Table 1.
Association between FGFR1 m-RNA expression and clinicopathological data of patients with ESCC.
| All patients | High FGFR1 expression | Low FGFR1 expression | ||
|---|---|---|---|---|
| Characteristics | No. (%) | No. (%) | No. (%) | p-value |
| Age | 0.369 | |||
| <70 | 132(9.0) | 68(93.2) | 64(88.8) | |
| ≥70 | 13(91.0) | 5(6.8) | 8(11.2) | |
| Gender | 0.751 | |||
| Male | 132 (91.0) | 67 (91.8) | 65(90.3) | |
| Female | 13(9.0) | 6(9.2) | 7(9.3) | |
| BMI | 0.197 | |||
| Low | 20(17.4) | 7(11.7) | 13(26.0) | |
| Mid | 82(71.3) | 47(78.3) | 35(64.8) | |
| High | 13(11.4) | 6(10.0) | 6(9.2) | |
| Smoking | 0.675 | |||
| No | 34(29.0) | 19 (26.0) | 15 (20.8) | |
| Yes | 111 (71.0) | 54(74.0) | 57(79.2) | |
| Drinking | 0.002* | |||
| Constantly | 87(60.0) | 53(72.6) | 33(45.8) | |
| Never or seldom | 58(40.0) | 20(27.4) | 39(55.2) | |
| TNM stage | 0.455 | |||
| II | 72(49.3) | 34(46.6) | 38(52.7) | |
| III | 73(50.7) | 39(53.4) | 34(47.3) | |
| T stage | 0.637 | |||
| 2 | 31(21.4) | 17(23.2) | 14(19.4) | |
| 3 | 96(66.2) | 46(63.0) | 50(69.4) | |
| 4 | 17(11.7) | 10(13.7) | 8(11.2) | |
| N stage | 0.589 | |||
| 0 | 61(42.1) | 29(39.7) | 32(44.4) | |
| 1 | 44(30.3) | 25(34.2) | 19(26.4) | |
| 2 | 40(27.6) | 19(26.1) | 21(29.0) | |
| WHO classification | 0.381 | |||
| G3 | 42(29.0) | 22(30.1) | 20(27.7) | |
| G2 | 98(67.6) | 50(68.5) | 48(66.7) | |
| G1 | 5(3.4) | 1(1.4) | 4(5.6) | |
| Pathological type | 0.856 | |||
| Ulcerated | 90(63.8) | 43(58.9) | 47(65.3) | |
| Medullary | 28(20.0) | 15(20.5) | 13(18.1) | |
| Protruded | 17(12.1) | 9(12.3) | 8(11.1) | |
| Other | 6(4.1) | 6(8.2) | 4(5.5) | |
| Location | 0.937 | |||
| Upper | 8(5.5) | 3(4.3) | 5(6.8) | |
| Middle | 64(44.1) | 31(44.9) | 33(44.6) | |
| Under | 71(50.4) | 35(48.6) | 36(48.7) | |
| Radiotherapy | 0.038* | |||
| No | 60(41.3) | 31(42.4) | 43(59.7) | |
| Yes | 85(58.7) | 42(57.6) | 29(40.2) | |
| Chemotherapy | 0.450 | |||
| No | 68(46.9) | 37(50.6) | 31(43.0) | |
| Yes | 77(53.1) | 36(49.3) | 41(57.0) |
*
χ2-test: P < 0.05. BMI, body mass index; FGFR1, fibroblast growth factor receptor-1