Table 1.
Patient Population | |
---|---|
n = 33 | |
Age (Years) | 57 (30–74) |
ECOG | |
0 | 26 (%79) |
1–2 | 7 (%21) |
Women | 8 (%24) |
Ethic origin | |
White | 33 (%100) |
Asian | 0 (%0) |
Black | 0 (%0) |
Positive family history for oncological diseases | 7 (%21) |
Second tumor disease | 4 (%12) |
Nicotiabusus | 14 (%42) |
Primary tumor side | |
Stomach | 11 (%33) |
GEJ | 22 (%67) |
Extend of disease at study entry | |
Locally advanced | 2 (%6) |
Metastatic | 31 (%94) |
Metastatic sites per patient | |
1 | 15 (%45) |
2 | 12 (%36) |
3–4 | 4 (%12) |
Chemothrapy regimen | |
TOGA | 23 (%70) |
Trastuzumab mono | 3 (%9) |
DCF | 2 (%6) |
EOX | 2 (%6) |
FOLFOX | 2 (%6) |
FOLFIRI | 1 (%3) |
Previous radiationtherapy | 4 (%12) |
Previous gastrectomy | 16 (%48) |
Herceptin line | |
1st | 23 (%70) |
2nd | 7 (%21) |
3rd | 3 (%9) |
Previous chemotherapy | |
EOX | 4 (%12) |
DCF | 3 (%9) |
HER2 status | |
ICH 3+ | 32 (%97) |
ICH 2+/FISH pos | 1 (%3) |
ECOG, Eastern Cooperative Oncology Groups; GEJ, gastroesophageal junction; ToGA, trastuzumab for gastric cancer; DCF, docetaxel/cisplatin/5-fluoroucil; EOX, epirubicin/oxaliplatin/capecitabine; FOLFOX, 5-fluoroucil/oxaliplatin; FOLFIRI, 5-fluoroucil/irinotecan; HER2, human epidermal growth factor receptor 2; ICH, immunohistochemistry; FISH, fluorescence in situ hybridization