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. 2018 Jan 16;13(1):e1422466. doi: 10.1080/15592324.2017.1422466

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Figure 2. — Putative mechanism of Mn tolerance in rice root. Right and left panels show normal and high Mn conditions, respectively. NRAMP5 is localized at the distal side of the exodermis and endodermis, while MTP9 is localized at the proximal side of both layers. MTP8.1 and MTP8.2 are localized to the tonoplast. Optimal Mn concentration in the root may be maintained via reduced uptake caused by the degradation of NRAMP5 and enhanced extrusion from cells caused by an increase in MTP9 accumulation, as well as constitutive vacuolar sequestration by MTP8.1 and MTP8.2.