Table 11.
Baseline to Treatment Period Laboratory Test Shift Tables for Patients from Randomized Placebo-Controlled Trials with Renal Dysfunction At Baseline (Blood Urea Nitrogen)
| Treatment period, confirmed observation | |||||
|---|---|---|---|---|---|
| BUN, mg/dL | Baseline | ≤22 | >22–31 | >31–44 | >44 |
| Placebo (N = 6) | ≤22 | 1 | 1 | 0 | 0 |
| >22–31 | 1 | 1 | 0 | 0 | |
| >31–44 | 0 | 1 | 0 | 0 | |
| >44 | 0 | 1 | 0 | 0 | |
| Total ASO (N = 12) | ≤22 | 3 | 0 | 0 | 0 |
| >22–31 | 0 | 4 | 0 | 0 | |
| >31–44 | 0 | 2 | 1 | 0 | |
| >44 | 0 | 1 | 0 | 1 | |
Bold values represent the middle line where no change was observed between baseline and the highest confirmed measure in the treatment period.