Table 9.

Baseline to Treatment Period Laboratory Test Shift Tables for Patients from Randomized Placebo-Controlled Trials with Renal Dysfunction At baseline (Creatinine)

		Treatment period, confirmed observation
Creatinine, mg/dL	Baseline	Unknown	≤1.4	>1.4–1.7	>1.7–2.1	>2.1–4.2	>4.2
Placebo (N = 6)	Unknown	0	0	0	0	0	0
	≤1.4	0	2	0	0	0	0
	>1.4–1.7	0	1	2	0	0	0
	>1.7–2.1	0	0	0	0	0	0
	>2.1–4.2	0	1	0	0	0	0
	>4.2	0	0	0	0	0	0
Total ASO (N = 12)	Unknown	0	0	0	0	0	0
	≤1.4	0	2	0	0	0	0
	>1.4–1.7	0	5	2	0	1	0
	>1.7–2.1	1	0	1	0	0	0
	>2.1–4.2	0	0	0	0	0	0
	>4.2	0	0	0	0	0	0

Bold values represent the middle line where no change was observed between baseline and the highest confirmed measure in the treatment period.