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. 2017 Dec 12;9(3):3069–3080. doi: 10.18632/oncotarget.23149

Figure 5. RFP inhibited the canonical Wnt signalling pathway.

Figure 5

(A) Representative Western blots and (B) the quantitative result of active/total β-catenin in neonatal cardiomyocytes (NRCMs) after transduced with indicated SiRNA and treated with hypoxia. (C) Representative Western blots and (D) the quantitative result of phosphorylated/total GSK-3β in neonatal cardiomyocytes (NRCMs) after transduced with indicated SiRNA and treated with hypoxia. N = 5 independent experiments in all groups. *P < 0.05, **P < 0.01 vs NO + Scr SiRNA, #P < 0.05 vs HO + Scr SiRNA. (E) Representative Western blots and (F) the quantitative result of active/total β-catenin in mouse left ventricles (LVs) one week after MI or sham surgery. (G) Representative Western blots and (H) the quantitative result of phosphorylated /total GSK-3β in mouse left ventricles (LVs) one week after MI or sham surgery. N = 5 per experimental group. All data are expressed as mean ± S.E.M. **P < 0.01 compared with sham + CFA, #P <0.05, ##P < 0.01 compared with MI + CFA.