Figure 7. Tubacin inhibits tumor growth by RT112 bladder cancer-derived cells.
(A) Tumors excised from mice that were generated following injection of 2 × 106 RT112 cells and either treated with vehicle or tubacin beginning on day 14 when tumor nodules became visible. (B) Dot plot showing weight of tumors in (A). (C) Tumors excised from mice that were generated following injection of 5 × 106 cells and either treated with vehicle or tubacin beginning on day 12 when established tumors were approximately 0.5 cm diameter. (D) Dot plot showing weight of tumors in (C). (E) Dot plot of the weight of vehicle- and tubacin-treated mice (N = 3) used in experiments associated with (C). Stippled line – mean weight of tubacin-treated mice, solid line – mean weight of vehicle-treated mice.