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. 2017 Dec 14;9(3):3292–3302. doi: 10.18632/oncotarget.23232

Table 2. Comparison of complete remission rates according to the plasma levels of BAFF and APRIL.

Univariate Multivariate*
Marker Group Level (ng/mL) HR (95% CI) P HR (95% CI) P
BAFF 1st tertile (n = 29) 0.7 ± 0.12 1 (Reference) 1 (Reference)
2nd tertile (n = 30) 0.9 ± 0.05 0.96 (0.514–1.785) 0.891 0.98 (0.465–2.066) 0.958
3rd tertile (n = 30) 1.2 ± 0.25 1.02 (0.546–1.905) 0.952 0.80 (0.360–1.770) 0.580
APRIL Undetectable (n = 53) 0 1 (Reference) 1 (Reference)
Low (n = 18) 0.3 (0.07–0.47) 0.76 (0.399–1.447) 0.403 0.83 (0.347–1.958) 0.662
High (n = 18) 1.6 (1.21–3.13) 0.40 (0.176–0.887) 0.024 0.23 (0.076–0.706) 0.010

*Adjusted for age, sex, hypertension, diabetes mellitus, baseline creatinine, albumin, cholesterol, urine protein to creatinine ratio, estimated glomerular filtration rate, the use of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, steroids, cyclophosphamides or other immunosuppressive agents, pathologic stage, and tubulointerstitial fibrosis.

Abbreviations: BAFF, B-cell activating factor; APRIL, a proliferation-inducing ligand; HR, hazard ratio; CI, confidence interval.