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. 2017 Dec 14;9(3):3338–3352. doi: 10.18632/oncotarget.23235

Table 1. Comparison of DTX concentration sin plasma and various tissues between TxR mice treated with DTX and combination of DTX and PIP.

Groups Tissue concentration (ng/mg) Plasma concentration
(ng/ml)
Tumor Brain Kidney Lung Liver
TxR-DTX (n = 10) 1.312 ± 0.754 0.022 ± 0.009 2.322 ± 1.447 5.158 ± 2.886 1.080 ± 0.763 703.847 ± 311.129
TxR-DTX+PIP (n = 10) 5.854 ± 5.510* 0.051 ± 0.047 5.980 ± 5.234 4.991 ± 3.133 2.782 ± 0.891** 1448.432 ± 698.493**

Note: Comparisons were conducted by Student’s T-test. *p < 0.05; **p < 0.01; ***p < 0.001.

Abbreviation: DTX = docetaxel; PIP = piperine.