Figure 4. AR knockdown promoted tumorigenic capacity and metastasis in mice.
Tumors formation and tumors size was shown in AR knockdown and control groups (A). Tumor growth curves in MCF7-277-ihRNA2 and MCF7-277-iluc groups after tumor xenotransplantation (B). Tumor formation rates in MCF7-277-ihRNA2 and MCF7-277-iluc groups (C). HE staining of livers without or with metastasis. Immunohistochemical staining of Ki67 in metastatic liver tissue (D).