Table 2. Characteristics of clones obtained by CRISPR/Cas9 mediated ATM inactivation in the mother’s fibroblasts.
Clone | Cas9 induced mutagenesis | Genotype | |
---|---|---|---|
On WT allele | On R32C allele | ||
#1 | None | None | R32C/WT |
#2 | None | None | R32C/WT |
#11 | 37bp deletion | None | –/WT |
#14 | None | Allele not amplified | R32C/– |