Table 1. Cumulative death and gross tumor occurrence in chickens inoculated with MSB-1 cells and its miRNA sponge-treated cells at different time points post inoculation.
Time point |
Category | MSB-1 | MSB-1+nc | MSB-1+sp | PBS |
---|---|---|---|---|---|
1 | Deaths | − | − | − | − |
Mortality | − | − | − | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
7 | Deaths | − | − | − | − |
Mortality | − | − | − | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
14 | Deaths | 1 | 1 | − | − |
Mortality | 4% | 4% | − | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
21 | Deaths | 3 | 4 | 1 | − |
Mortality | 12% | 16% | 4% | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
30 | Deaths | 4 | 5 | 2 | − |
Mortality | 16% | 20% | 8% | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
45 | Deaths | 5 | 6 | 3 | − |
Mortality | 20% | 24% | 12% | − | |
Gross tumours | − | − | − | − | |
Tumour incidence | − | − | − | − | |
60 | Deaths | 7 | 8 | 4 | − |
Mortality | 28% | 32% | 16% | − | |
Gross tumours | 3 | 2 | − | − | |
Tumour incidence | 12% | 8% | − | − |
Total of 10 birds in PBS group, and the other group was 25.
–, No death or gross tumors were observed at corresponding time points post-inoculation.