Figure 1. Effect of STAT3 inhibition in GSC lines.

(A) GSC viability was assessed by MTS assay after 5 days of Stattic or WP1066 treatment. The half maximal inhibitory concentrations IC50 and IC20 are indicated in the panel. Each point represents the mean of at least 3 independent experiments. Error bars show ± the standard error of the mean. (B) Western Blot analysis of STAT3 phosphorylation status after treatment with indicated doses of each inhibitor. No major modification of total STAT3 expression was observed. Actin was used as internal control. This experiment was repeated 3 times.